Repression of COUP-TFI Improves Bone Marrow-Derived Mesenchymal Stem Cell Differentiation into Insulin-Producing Cells

• Main Authors: Tao Zhang (Author), Xiao-Hang Li (Author), Dian-Bao Zhang (Author), Xiao-Yu Liu (Author), Feng Zhao (Author), Xue-Wen Lin (Author), Rui Wang (Author), Hong-Xin Lang (Author), Xi-Ning Pang (Author)
• Format: Book
• Published: Elsevier, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Identifying molecular mechanisms that regulate insulin expression in bone marrow-derived mesenchymal stem cells (bmMSCs) can provide clues on how to stimulate the differentiation of bmMSCs into insulin-producing cells (IPCs), which can be used as a therapeutic approach against type 1 diabetes (T1D)....