Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways

• Main Authors: Li-fei Gu (Author), Hai-tao Ge (Author), Lei Zhao (Author), Yu-jing Wang (Author), Fan Zhang (Author), Hai-tao Tang (Author), Zheng-yu Cao (Author), Bo-yang Yu (Author), Cheng-zhi Chai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is the final common pathological manifestation of almost all progressive chronic kidney diseases (CKD). Transient receptor potential canonical (TRPC) channels, especially TRPC3/6, were proposed to be essential therapeutic targets for kidney injury. Huangkui capsule (HKC), an important...