Tumor Necrosis Factor and Schistosoma mansoni egg antigen omega-1 shape distinct aspects of the early egg-induced granulomatous response.

• Main Authors: Kevin K Takaki (Author), Francisco J Roca (Author), Gabriele Schramm (Author), Ruud H P Wilbers (Author), Wannaporn Ittiprasert (Author), Paul J Brindley (Author), Gabriel Rinaldi (Author), Matthew Berriman (Author), Lalita Ramakrishnan (Author), Antonio J Pagán (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infections by schistosomes result in granulomatous lesions around parasite eggs entrapped within the host tissues. The host and parasite determinants of the Schistosoma mansoni egg-induced granulomatous response are areas of active investigation. Some studies in mice implicate Tumor Necrosis Factor...