Clinically relevant orthotopic xenograft models of patient-derived glioblastoma in zebrafish

• Главные авторы: Xiaolin Ai (Автор), Zengpanpan Ye (Автор), Chaoxin Xiao (Автор), Jian Zhong (Автор), Joseph J. Lancman (Автор), Xuelan Chen (Автор), Xiangyu Pan (Автор), Yu Yang (Автор), Lin Zhou (Автор), Xiang Wang (Автор), Huashan Shi (Автор), Dongmei Zhang (Автор), Yuqin Yao (Автор), Dan Cao (Автор), Chengjian Zhao (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2022-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

An accurate prediction of the intracranial infiltration tendency and drug response of individual glioblastoma (GBM) cells is essential for personalized prognosis and treatment for this disease. However, the clinical utility of mouse patient-derived orthotopic xenograft (PDOX) models remains limited...