Clinically relevant orthotopic xenograft models of patient-derived glioblastoma in zebrafish

• Main Authors: Xiaolin Ai (Author), Zengpanpan Ye (Author), Chaoxin Xiao (Author), Jian Zhong (Author), Joseph J. Lancman (Author), Xuelan Chen (Author), Xiangyu Pan (Author), Yu Yang (Author), Lin Zhou (Author), Xiang Wang (Author), Huashan Shi (Author), Dongmei Zhang (Author), Yuqin Yao (Author), Dan Cao (Author), Chengjian Zhao (Author)
• Format: Book
• Published: The Company of Biologists, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An accurate prediction of the intracranial infiltration tendency and drug response of individual glioblastoma (GBM) cells is essential for personalized prognosis and treatment for this disease. However, the clinical utility of mouse patient-derived orthotopic xenograft (PDOX) models remains limited...