Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection.

• Auteurs principaux: Teresa G Martins (Auteur), Gabriela Trigo (Auteur), Alexandra G Fraga (Auteur), José B Gama (Auteur), Adhemar Longatto-Filho (Auteur), Margarida Saraiva (Auteur), Manuel T Silva (Auteur), António G Castro (Auteur), Jorge Pedrosa (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

BACKGROUND: Buruli ulcer (BU) is a necrotizing disease of the skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. It has been suggested that the immune response developed during the recommended rifampicin/streptomycin (RS) antibiotherapy is protective, contributing to bacterial clea...