Solid dispersion-based pellet for colon delivery of tacrolimus through time- and pH-dependent layer coating: preparation, in vitro and in vivo studies

The intent of the present investigation is to develop and evaluate colon-specific coated tacrolimus solid dispersion pellet (SDP) that retards drug release in the stomach and small intestine but progressively releases in the colon. Tacrolimus-SDP was prepared by extrusion-spheronization technology a...

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Bibliographic Details
Main Authors: Jian Guo (Author), Huihui Fang (Author), Shuangying Gui (Author), Yuzhe Huang (Author)
Format: Book
Published: Universidade de São Paulo, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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