The Function and Roles of ADAMTS-7 in Inflammatory Diseases

• Main Authors: Yuying Zhang (Author), Jiqiang Lin (Author), Fanhua Wei (Author)
• 格式: 圖書
• 出版: Hindawi Limited, 2015-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The ADAMTS proteinases are a group of multidomain and secreted metalloproteinases containing the thrombospondin motifs. ADAMTS-7 is a member of ADAMTS family and plays a crucial role in the pathogenesis of arthritis. Overexpression of ADAMTS-7 gene promotes the breakdown of cartilage oligomeric matr...