Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome

• Main Authors: Patricia R. Shaw (Author), Jenny A. Klein (Author), Nadine M. Aziz (Author), Tarik F. Haydar (Author)
• פורמט: ספר
• יצא לאור: The Company of Biologists, 2020-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Mouse models of Down syndrome (DS) have been invaluable tools for advancing knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts(1716)65Dn (Ts65Dn) mouse is one of the most commonly used models as it recapitulates many of the phenotypes seen in individuals with...