Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome

• Main Authors: P. Galozzi (Author), O. Negm (Author), E. Greco (Author), N. Alkhattabi (Author), A. Gava (Author), P. Sfriso (Author), L. Fairclough (Author), I. Todd (Author), P. Tighe (Author), L. Punzi (Author)
• Format: Book
• Published: PAGEPress Publications, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective was to study both ex vivo and in vitro secretion of pro-inflammatory cytokines in patients affected by Blau syndrome (BS) and carrying p.E383K mutation in the CARD15/NOD2 gene associated with the disease. For ex vivo studies, peripheral blood mononuclear cells (PBMCs), serum from three...