Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration

• Main Authors: Xin Xu (Author), Ni Han (Author), Fangkun Zhao (Author), Ruoyue Fan (Author), Qingguo Guo (Author), Xuefei Han (Author), Ying Liu (Author), Guangzuo Luo (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Retinal neovascularization (RNV) is primarily driven by vascular endothelial growth factor (VEGF). However, current anti-VEGF therapies are limited by short half-lives and repeated injections, which reduce patient quality of life and increase medical risks. Additionally, not all patients benefit fro...