Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples

• Hoofdauteurs: Louise de Schaetzen van Brienen (Auteur), Maarten Larmuseau (Auteur), Kim Van der Eecken (Auteur), Frederic De Ryck (Auteur), Pauline Robbe (Auteur), Anna Schuh (Auteur), Jan Fostier (Auteur), Piet Ost (Auteur), Kathleen Marchal (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2020-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Research grade Fresh Frozen (FF) DNA material is not yet routinely collected in clinical practice. Many hospitals, however, collect and store Formalin Fixed Paraffin Embedded (FFPE) tumor samples. Consequently, the sample size of whole genome cancer cohort studies could be increa...