Adult and pediatric physiologically‐based biopharmaceutics modeling to explain lamotrigine immediate release absorption process

• Main Authors: Edilainy Rizzieri Caleffi‐Marchesini (Author), Amanda Antunes Herling (Author), Julia Macente (Author), Rodolfo Hernandes Bonan (Author), Priscila deFreitas Lima (Author), Rafaela Moreno (Author), Veriano Alexandre (Author), Nitin Bharat Charbe (Author), Fernanda Belincanta Borghi‐Pangoni (Author), Rodrigo Cristofoletti (Author), Andréa Diniz (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Physiologically‐based biopharmaceutics modeling (PBBM) has potential to accelerate the development of new drug and formulations. An important application of PBBM is for special populations such as pediatrics that have pharmacokinetics dependent on the maturation process. Lamotrigine (LTG) i...