Modeling the subcutaneous pharmacokinetics of antibodies co‐administered with rHuPH20

Abstract Predicting the subcutaneous (SC) pharmacokinetics (PK) of antibodies in humans is challenging, with clinical data currently being the only reliable data source for modeling SC absorption and bioavailability. Recombinant human hyaluronidase PH20 (rHuPH20) is an enzyme that facilitates SC del...

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Main Authors: Ryan P. Nolan (Author), Marie A. Printz (Author)
Format: Book
Published: Wiley, 2024-04-01T00:00:00Z.
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