Combined use of microbubbles of various sizes and single‐transducer dual‐frequency ultrasound for safe and efficient inner ear drug delivery

• Main Authors: Ai‐Ho Liao (Author), Chih‐Hung Wang (Author), Bo‐Han Wang (Author), Yi‐Chun Lin (Author), Ho‐Chiao Chuang (Author), Hao‐Li Liu (Author), Cheng‐Ping Shih (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We have previously applied ultrasound (US) with microbubbles (MBs) to enhance inner ear drug delivery, with most experiments conducted using single‐frequency, high‐power density US, and multiple treatments. In the present study, the treatment efficacy was enhanced and safety concerns were a...