Cholesterol-Based Nanovesicles Enhance the In Vitro Cytotoxicity, Ex Vivo Intestinal Absorption, and In Vivo Bioavailability of Flutamide

• Main Authors: Mohamed A. Ali (Author), Magdy I. Mohamed (Author), Mohamed A. Megahed (Author), Tamer M. Abdelghany (Author), Khalid M. El-Say (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Critical adverse effects and frequent administration, three times per day, limit the use of flutamide (FLT) as a chemotherapeutic agent in the treatment of prostate cancer. Therefore, our research aimed to develop new cholesterol-based nanovesicles for delivering FLT to malignant cells in an endeavo...