Hypomethylation of NLRP3 gene promoter discriminates glucocorticoid‐resistant from glucocorticoid‐sensitive idiopathic nephrotic syndrome patients

• Main Authors: Marianna Lucafò (Author), Simona Granata (Author), Erik J. Bonten (Author), Robert McCorkle (Author), Gabriele Stocco (Author), Chiara Caletti (Author), Davide Selvestrel (Author), Alessio Cozzarolo (Author), Chan Zou (Author), Eva Cuzzoni (Author), Andrea Pasini (Author), Giovanni Montini (Author), Giovanni Gambaro (Author), Giuliana Decorti (Author), William Evans (Author), Gianluigi Zaza (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract To assess whether NLRP3 gene promoter methylation was able to discriminate glucocorticoid (GC)‐resistant from GC‐sensitive idiopathic nephrotic syndrome (INS), patients with minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS), we measured the methylation level of NLRP3...