Therapeutic enhancement of protective immunity during experimental leishmaniasis.

• Main Authors: Senad Divanovic (Author), Aurelien Trompette (Author), Jamie I Ashworth (Author), Marepalli B Rao (Author), Christopher L Karp (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis remains a significant cause of morbidity and mortality in the tropics. Available therapies are problematic due to toxicity, treatment duration and emerging drug resistance. Mouse models of leishmaniasis have demonstrated that disease outcome depends critically on the balance between ef...