Indirect immunofluorescence assay for the simultaneous detection of antibodies against clinically important old and new world hantaviruses.

• Main Authors: Sabine Lederer (Author), Erik Lattwein (Author), Merle Hanke (Author), Karen Sonnenberg (Author), Winfried Stoecker (Author), Åke Lundkvist (Author), Antti Vaheri (Author), Olli Vapalahti (Author), Paul K S Chan (Author), Heinz Feldmann (Author), Daryl Dick (Author), Jonas Schmidt-Chanasit (Author), Paula Padula (Author), Pablo A Vial (Author), Raluca Panculescu-Gatej (Author), Cornelia Ceianu (Author), Paul Heyman (Author), Tatjana Avšič-Županc (Author), Matthias Niedrig (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to detect serum antibodies against clinically important Old and New World hantaviruses simultaneously, multiparametric indirect immunofluorescence assays (IFAs) based on biochip mosaics were developed. Each of the mosaic substrates consisted of cells infected with one of the virus types Han...