Generic Hockey-Stick Model for Estimating Benchmark Dose and Potency: Performance Relative to BMDS and Application to Anthraquinone

• Auteur principal: Kenneth T. Bogen (Auteur)
• Format: Livre
• Publié: SAGE Publishing, 2011-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Benchmark Dose Model software (BMDS), developed by the U.S. Environmental Protection Agency, involves a growing suite of models and decision rules now widely applied to assess noncancer and cancer risk, yet its statistical performance has never been examined systematically. As typically applied, BMD...