Brevinin-2GHk from <i>Sylvirana guentheri</i> and the Design of Truncated Analogs Exhibiting the Enhancement of Antimicrobial Activity

• Main Authors: Guanzhu Chen (Author), Yuxi Miao (Author), Chengbang Ma (Author), Mei Zhou (Author), Zhanzhong Shi (Author), Xiaoling Chen (Author), James F. Burrows (Author), Xinping Xi (Author), Tianbao Chen (Author), Lei Wang (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brevinins are an important antimicrobial peptide (AMP) family discovered in the skin secretions of Ranidae frogs. The members demonstrate a typical C-terminal ranabox, as well as a diverse range of other structural characteristics. In this study, we identified a novel brevinin-2 peptide from the ski...