Identification of potential immunomodulators from Pulsatilla decoction that act on therapeutic targets for ulcerative colitis based on pharmacological activity, absorbed ingredients, and in-silico molecular docking

• Главные авторы: Li-rong Deng (Автор), Qian Han (Автор), Min Zou (Автор), Fang-jun Chen (Автор), Chang-yin Huang (Автор), Yi-ming Zhong (Автор), Qian-yan Wu (Автор), Brian Tomlinson (Автор), Yan-hong Li (Автор)
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• Опубликовано: BMC, 2022-11-01T00:00:00Z.
• Предметы: article
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Abstract Background Pulsatilla decoction (Bai-Tou-Weng-Tang, BTWT) is a classic formula prescription of a traditional Chinese medicine that is used to treat ulcerative colitis (UC). However, its active components and underlying mechanism of action remain unclear. In the present study, we aimed to id...