Identification of potential immunomodulators from Pulsatilla decoction that act on therapeutic targets for ulcerative colitis based on pharmacological activity, absorbed ingredients, and in-silico molecular docking

• Main Authors: Li-rong Deng (Author), Qian Han (Author), Min Zou (Author), Fang-jun Chen (Author), Chang-yin Huang (Author), Yi-ming Zhong (Author), Qian-yan Wu (Author), Brian Tomlinson (Author), Yan-hong Li (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pulsatilla decoction (Bai-Tou-Weng-Tang, BTWT) is a classic formula prescription of a traditional Chinese medicine that is used to treat ulcerative colitis (UC). However, its active components and underlying mechanism of action remain unclear. In the present study, we aimed to id...