Microbiological Profiles of Dental Implants in Metabolic Syndrome Patients: A Case-Control Study

• Main Authors: Bianca Di Murro (Author), Marta Moretti (Author), Enrico De Smaele (Author), Claudio Letizia (Author), Carla Lubrano (Author), Pier Carmine Passarelli (Author), Antonio D'Addona (Author), Giorgio Pompa (Author), Piero Papi (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

There is a lack of knowledge on the possible influence of systemic conditions on peri-implantitis. The aim of this case-control study is to evaluate the difference in terms of oral pathogens' concentrations in the peri-implant sulcus of a group of patients affected by metabolic syndrome (Mets) compared to healthy subjects. For each patient, peri-implant sulcular biofilm samples were obtained by inserting two sterile endodontic paper points in the deepest aspect of the peri-implant sulcus for 30 s. The quantitative real-time polymerase chain reaction was performed to evaluate total bacterial counts of six pathogens. Patients were screened for peri-implant diseases and clinical and radiographic parameters were recorded. A total of 50 patients was enrolled in the study, 25 affected by Mets and 25 healthy. Significantly higher bacterial counts were discovered for <i>Aggregatibacter actinomycetemcomitans</i> (<i>p</i> = 0.0008), <i>Prevotella intermedia</i> (<i>p</i> = 0.0477) and <i>Staphylococcus aureus</i> (<i>p</i> = 0.034) in MetS patients compared to healthy subjects. Performing a sub-group analysis, considering peri-implant status and dividing patients by MetS diagnosis, no statistically significant (<i>p</i> < 0.05) differences were found. For the first time, a correlation between MetS presence and a greater prevalence of some bacterial species in the peri-implant sulcus was reported, irrespectively from peri-implant status (health vs. disease).

Item Description

10.3390/antibiotics10040452
2079-6382