Pioglitazone is effective for multiple phenotyepes of the Zucker fa/fa rat with polycystc ovary morphology and insulin resistance

• Main Authors: Miyuki Morishita (Author), Toshiaki Endo (Author), Tsuyoshi Baba (Author), Yoshika Kuno (Author), Keiko Ikeda (Author), Tamotsu Kiya (Author), Hiroyuki Honnma (Author), Tsuyoshi Saito (Author)
• Format: Book
• Published: BMC, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hyperandrogenism and insulin resistance may be related to the etiology of PCOS. Zucker fa/fa rats with polycystic ovary are obese, have insulin resistance without diabetes mellitus or hyperandrogenism and can be utilized as PCOS model rats without effects of hyperandrogenemia. PC...