Crystal-liquid Fugacity Ratio as a Surrogate Parameter for Intestinal Permeability

• Автори: Parvin Zakeri-Milani (Автор), Zohreh Fasihi (Автор), Jafar Akbari (Автор), Ensieh Jannatabadi (Автор), Mohammad Barzegar-Jalali (Автор), Raimar Loebenberg (Автор), Hadi Valizadeh (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: We assessed the feasibility of using crystal-liquid fugacity ratio (CLFR) as an alternative parameter for intestinal permeability in the biopharmaceutical classification (BCS) of passively absorbed drugs. Methods: Dose number, fraction of dose absorbed, intestinal permeability, and intri...