The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)

• Главные авторы: Dou Yeon Youn (Автор), Alus M. Xiaoli (Автор), Haihong Zong (Автор), Junichi Okada (Автор), Li Liu (Автор), Jacob Pessin (Автор), Jeffrey E. Pessin (Автор), Fajun Yang (Автор)
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• Опубликовано: Elsevier, 2021-06-01T00:00:00Z.
• Предметы: article
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Objective: Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accumulation in the liver by upregulating the expressi...