Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells

• Main Authors: Seok Hui Kang (Author), Sang Woon Kim (Author), Keuk Jun Kim (Author), Kyu Hyang Cho (Author), Jong Won Park (Author), Chan-Duck Kim (Author), Jun Young Do (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background : We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs).Methods : We performed in vitro studies (cytotoxicity, cell morphology, and western blot analyses) on...