Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs

• প্রধান লেখক: Miklós Tamás Katona (লেখক), Lili Nagy-Katona (লেখক), Réka Szabó (লেখক), Enikő Borbás (লেখক), Péter Tonka-Nagy (লেখক), Krisztina Takács-Novák (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The purpose of this study was to investigate the applicability of the Gastrointestinal Simulator (GIS), a multi-compartmental dissolution model, to predict the in vivo performance of Biopharmaceutics Classification System (BCS) Class IIa compounds. As the bioavailability enhancement of poorly solubl...