Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs

The purpose of this study was to investigate the applicability of the Gastrointestinal Simulator (GIS), a multi-compartmental dissolution model, to predict the in vivo performance of Biopharmaceutics Classification System (BCS) Class IIa compounds. As the bioavailability enhancement of poorly solubl...

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Main Authors: Miklós Tamás Katona (Author), Lili Nagy-Katona (Author), Réka Szabó (Author), Enikő Borbás (Author), Péter Tonka-Nagy (Author), Krisztina Takács-Novák (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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