In Vitro and In Vivo Characterisation of a Mucoadhesive Buccal Film Loaded with Doxycycline Hyclate for Topical Application in Periodontitis

• Main Authors: Elena Dinte (Author), Dana Maria Muntean (Author), Vlad Andrei (Author), Bianca Adina Boșca (Author), Cristian Mircea Dudescu (Author), Lucian Barbu-Tudoran (Author), Gheorghe Borodi (Author), Sanda Andrei (Author), Adrian Florin Gal (Author), Vasile Rus (Author), Luciana-Mădălina Gherman (Author), Oana Cadar (Author), Reka Barabas (Author), Mihaela Niculae (Author), Aranka Ilea (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mucoadhesive films loaded with doxycycline hyclate (Doxy Hyc), consisting of mixtures of hydroxypropylmethyl cellulose (HPMC) E3, K4 and polyacrylic acid (Carbopol 940), were prepared by casting method, aiming to design a formulation intended for application in the oral cavity. The obtained film for...