Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin

• Main Authors: Ran Wang (Author), Sijing Zhou (Author), Peipei Wu (Author), Min Li (Author), Xing Ding (Author), Li Sun (Author), Xuan Xu (Author), Xuexin Zhou (Author), Luqian Zhou (Author), Chao Cao (Author), Guanghe Fei (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-coding RNAs play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). The aim of this study was to characterize the therapeutic role of melatonin as well as the underlying molecular mechanism (its effects on the expression of H19 and its downstream signaling pathways)...