Ex vivo infection of murine precision-cut lung tissue slices with Mycobacterium abscessus: a model to study antimycobacterial agents

• Main Authors: Carmen Amelia Molina-Torres (Author), Oscar Noé Flores-Castillo (Author), Irma Edith Carranza-Torres (Author), Nancy Elena Guzmán-Delgado (Author), Ezequiel Viveros-Valdez (Author), Lucio Vera-Cabrera (Author), Jorge Ocampo-Candiani (Author), Julia Verde-Star (Author), Jorge Castro-Garza (Author), Pilar Carranza-Rosales (Author)
• Format: Book
• Published: BMC, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Multidrug-resistant infections due to Mycobacterium abscessus often require complex and prolonged regimens for treatment. Here, we report the evaluation of a new ex vivo antimicrobial susceptibility testing model using organotypic cultures of murine precision-cut lung slices, an...