A PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND REDUCES CELL VIABILITY AND INDUCES APOPTOSIS IN DIFFERENT HEMATOLOGICAL MALIGNANCIES

• Main Authors: Ilaria Laurenzana (Author), Antonella Caivano (Author), Francesco La Rocca (Author), Stefania Trino (Author), Luciana De Luca (Author), Francesca D'Alessio (Author), Silvia Schenone (Author), Geppino Falco (Author), Maurizio Botta (Author), Luigi Del Vecchio (Author), Pellegrino Musto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular targeted therapies are based upon drugs acting on tumors by interfering with specific targets involved in growth and spread of cancer. Many targeted therapies were approved by Food and Drug Administration as standard treatment, others were introduced into preclinical or clinical studies on...