Cathepsin L promotes chemresistance to neuroblastoma by modulating serglycin

• Main Authors: Xiaohuan Du (Author), Leyun Ding (Author), Shungen Huang (Author), Fang Li (Author), Yinghui Yan (Author), Ruze Tang (Author), Xinyuan Ding (Author), Zengyan Zhu (Author), Wenjuan Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cathepsin L (CTSL), a lysosomal acid cysteine protease, is found to play a critical role in chemosencitivity and tumor progression. However, the potential roles and molecular mechanisms of CTSL in chemoresistance in neuroblastoma (NB) are still unclear. In this study, the correlation between clinica...