Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors

• Main Authors: Lauren M DePoy (Author), Riley E Perszyk (Author), Kelsey S Zimmermann (Author), Anthony J Koleske (Author), Shannon Leigh Gourley (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cocaine and amphetamine remodel dendritic spines within discrete cortico-limbic brain structures including the orbitofrontal cortex (oPFC). Whether dendrite structure is similarly affected, and whether pre-existing cellular characteristics influence behavioral vulnerabilities to drugs of abuse, rema...