Lactose-Gated Mesoporous Silica Particles for Intestinal Controlled Delivery of Essential Oil Components: An In Vitro and In Vivo Study

• Main Authors: Elisa Poyatos-Racionero (Author), Isabel González-Álvarez (Author), Paola Sánchez-Moreno (Author), Leopoldo Sitia (Author), Francesca Gatto (Author), Pier Paolo Pompa (Author), Elena Aznar (Author), Marta González-Álvarez (Author), Ramón Martínez-Máñez (Author), María Dolores Marcos (Author), Andrea Bernardos (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesoporous silica microparticles functionalized with lactose for the specific release of essential oil components (EOCs) in the small intestine are presented. In vitro and in vivo intestinal models were applied to validate the microparticles (M41-EOC-L), in which the presence of lactase acts as the...