Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers

• Prif Awduron: Koerber H Richard (Awdur), McIlwrath Sabrina L (Awdur), Lawson Jeffrey J (Awdur), Malin Sacha A (Awdur), Anderson Collene E (Awdur), Jankowski Michael P (Awdur), Davis Brian M (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: SAGE Publishing, 2010-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Previous studies have shown that the TRPV1 ion channel plays a critical role in the development of heat hyperalgesia after inflammation, as inflamed TRPV1-/- mice develop mechanical allodynia but fail to develop thermal hyperalgesia....