Quantitative understanding of HepaRG cells during drug‐induced intrahepatic cholestasis through changes in bile canaliculi dynamics

• Main Authors: Rie Sonoi (Author), Yoshihisa Hagihara (Author)
• Format: Knjiga
• Izdano: Wiley, 2022-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract An understanding of the quantitative relationship between bile canaliculus (BC) dynamics and the disruption of tight junctions (TJs) during drug‐induced intrahepatic cholestasis may lead to new strategies aimed at drug development and toxicity testing. To investigate the relationship betwee...