Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1

Abstract Induced pluripotent stem cells (iPSCs) were first established from differentiated somatic cells by gene introduction of key transcription factors, OCT4, SOX2, KLF4, and c-MYC, over a decade ago. Although iPSCs can be applicable for regenerative medicine, disease modeling and drug screening,...

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Main Authors: Tomoaki Ishida (Author), Shu Nakao (Author), Tomoe Ueyama (Author), Yukihiro Harada (Author), Teruhisa Kawamura (Author)
Format: Book
Published: BMC, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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