Silencing of lncRNA UCA1 inhibited the pathological progression in PCOS mice through the regulation of PI3K/AKT signaling pathway

• المؤلفون الرئيسيون: Dongyong Yang (مؤلف), Yanqing Wang (مؤلف), Yajing Zheng (مؤلف), Fangfang Dai (مؤلف), Shiyi Liu (مؤلف), Mengqin Yuan (مؤلف), Zhimin Deng (مؤلف), Anyu Bao (مؤلف), Yanxiang Cheng (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2021-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) is the most common hormonal disorder among reproductive-aged women worldwide, however, the mechanisms and progression of PCOS still unclear due to its heterogeneous nature. Using the human granulosa-like tumor cell line (KGN) and PCOS mice model,...