Silencing of lncRNA UCA1 inhibited the pathological progression in PCOS mice through the regulation of PI3K/AKT signaling pathway

• Main Authors: Dongyong Yang (Author), Yanqing Wang (Author), Yajing Zheng (Author), Fangfang Dai (Author), Shiyi Liu (Author), Mengqin Yuan (Author), Zhimin Deng (Author), Anyu Bao (Author), Yanxiang Cheng (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) is the most common hormonal disorder among reproductive-aged women worldwide, however, the mechanisms and progression of PCOS still unclear due to its heterogeneous nature. Using the human granulosa-like tumor cell line (KGN) and PCOS mice model,...