Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer

• Главные авторы: Wujian Zheng (Автор), Qi Feng (Автор), Jiao Liu (Автор), Yanke Guo (Автор), Lvfen Gao (Автор), Ruiman Li (Автор), Meng Xu (Автор), Guizhen Yan (Автор), Zhinan Yin (Автор), Shuai Zhang (Автор), Shuangping Liu (Автор), Changliang Shan (Автор)
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• Опубликовано: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Предметы: article
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Cisplatin (DDP) is currently one of the most commonly used chemotherapeutic drugs for treating ovarian and lung cancer. However, resistance to cisplatin is common and it often leads to therapy failure. In addition, the precise mechanism of cisplatin resistance is still in its infancy. In this study,...