Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial.

• Main Authors: Benjamin Speich (Author), Shaali M Ame (Author), Said M Ali (Author), Rainer Alles (Author), Jan Hattendorf (Author), Jürg Utzinger (Author), Marco Albonico (Author), Jennifer Keiser (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The currently used anthelmintic drugs, in single oral application, have low efficacy against Trichuris trichiura infection, and hence novel anthelmintic drugs are needed. Nitazoxanide has been suggested as potential drug candidate.The efficacy and safety of a single oral dose of nitazoxanide (1,000...