Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease

• Autors principals: Ming Yang (Autor), Jiayi Lv (Autor), Chanjuan Gong (Autor), Cheng Xue (Autor), Lili Fu (Autor), Shunjie Chen (Autor), Changlin Mei (Autor)
• Format: Llibre
• Publicat: Karger Publishers, 2024-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Introduction: It has been reported that rapamycin inhibited inflammation in renal interstitial diseases. We therefore hypothesized that rapamycin could attenuate inflammation in polycystic kidney disease (PKD). Methods: Han:SPRD rats were treated with rapamycin by daily gavage from 4 weeks to 12 wee...