Triple-Antibiotic Combination Exerts Effective Activity against <i>Mycobacterium avium</i> subsp. <i>hominissuis</i> Biofilm and Airway Infection in an In Vivo Murine Model

• Main Authors: Elliot M. Offman (Author), Amy Leestemaker-Palmer (Author), Reza Fathi (Author), Bailey Keefe (Author), Aida Bibliowicz (Author), Gilead Raday (Author), Luiz E. Bermudez (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Slow-growing nontuberculous mycobacteria (NTMs) are highly prevalent and routinely cause opportunistic intracellular infectious disease in immunocompromised hosts. Methods: The activity of the triple combination of antibiotics, clarithromycin (CLR), rifabutin (RFB), and clofazimine (CFZ)...