SIRT6 reduces the symptoms of premature ovarian failure and alleviates oxidative stress and apoptosis in granulosa cells by degrading p66SHC via H3K9AC

Context Substantial evidence suggests that ovarian oxidative stress can result in severe ovarian dysfunction.Objective The purpose of this article is to investigate the potential of SIRT6 in alleviating premature ovarian failure (POF) by inhibiting oxidative stress.Methods To mimic POF, mice were ad...

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Main Authors: Chuan Shen (Author), Yongmei Jiang (Author), Jia Lin (Author), Yibei He (Author), Yue Liu (Author), Dingzhi Fang (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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