The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome

• Auteurs principaux: Chen Jiande DZ (Auteur), Zhou Shufang (Auteur), Shenoy Mohan (Auteur), Winston John H (Auteur), Xu Guang-Yin (Auteur), Pasricha Pankaj J (Auteur)
• Format: Livre
• Publié: SAGE Publishing, 2009-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a role for hydrogen sulfide (H₂S) in pain si...