The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome

• Main Authors: Chen Jiande DZ (Author), Zhou Shufang (Author), Shenoy Mohan (Author), Winston John H (Author), Xu Guang-Yin (Author), Pasricha Pankaj J (Author)
• Formato: Livro
• Publicado em: SAGE Publishing, 2009-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a role for hydrogen sulfide (H₂S) in pain si...