Atypical antipsychotics induce human osteoblasts apoptosis via Wnt/β-catenin signaling

• Main Authors: Peifan Li (Author), Yiming Wang (Author), Xingde Liu (Author), Zhen Zhou (Author), Jun Wang (Author), Haiyan Zhou (Author), Lei Zheng (Author), Lixia Yang (Author)
• Format: Book
• Published: BMC, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background There is evidence that atypical antipsychotics (APs) increase risk of osteoporosis in schizophrenia patients, however the mechanism is unclear. The aim of the study was to explore the molecular mechanisms about Wnt/β-catenin signal pathway underlying the osteal side effects of AP...