Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

• Príomhchruthaitheoirí: Yan Wang (Údar), Di Qin (Údar), Yiyao Gao (Údar), Yunxin Zhang (Údar), Yao Liu (Údar), Lihong Huang (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Background: Osteosarcoma (OS) is a common primary tumor with extensive heterogeneity. In this study, we used single-cell RNA sequencing (scRNA-seq) and network pharmacology to analyze effective targets for Osteosarcoma treatment.Methods: The cell heterogeneity of the Osteosarcoma single-cell dataset...