Dose of antivenom for the treatment of snakebite with neurotoxic envenoming: Evidence from a randomised controlled trial in Nepal.

• Main Authors: Emilie Alirol (Author), Sanjib Kumar Sharma (Author), Anup Ghimire (Author), Antoine Poncet (Author), Christophe Combescure (Author), Chabilal Thapa (Author), Vijaya Prasad Paudel (Author), Kalidas Adhikary (Author), Walter Robert Taylor (Author), David Warrell (Author), Ulrich Kuch (Author), François Chappuis (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Currently, there is inadequate evidence on which to base clinical management of neurotoxic snakebite envenoming, especially in the choice of initial antivenom dosage. This randomised controlled trial compared the effectiveness and safety of high versus low initial antivenom dosage in vict...