Hu.4-1BB-Fc fusion protein inhibits allergic inflammation and airway hyperresponsiveness in a murine model of asthma
Purpose4-1BB (CD 137) is a costimulatory molecule expressed on activated T-cells. Repression by 4-1BB is thought to attenuate Th2-mediated allergic reactions. The aim of this study was to investigate the effect of 4-1BB on allergic airway inflammation in a murine asthma model.MethodsBALB/c mice were...
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Autores principales: | , , , , , , , |
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Formato: | Libro |
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Korean Pediatric Society,
2011-09-01T00:00:00Z.
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Número de Clasificación: |
A1234.567 |
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