Combined Genetic Association and Differed Expression Analysis of UBE2L3 Uncovers a Genetic Regulatory Role of (Immuno)proteasome in IgA Nephropathy

• Main Authors: Lin-Lin Xu (Author), Ting Gan (Author), Yang Li (Author), Pei Chen (Author), Su-Fang Shi (Author), Li-Jun Liu (Author), Ji-Cheng Lv (Author), Hong Zhang (Author), Xu-Jie Zhou (Author)
• Format: Book
• Published: Karger Publishers, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: IgA nephropathy (IgAN) is a leading cause of end-stage renal disease. The exact pathogenesis of IgAN is not well defined, but some genetic studies have led to a novel discovery that the (immuno)proteasome probably plays an important role in IgAN. Methods: We firstly analyzed the associ...