Design, synthesis, molecular docking, and in vitro studies of 2-mercaptoquinazolin-4(3H)-ones as potential anti-breast cancer agents

• Үндсэн зохиолчид: Manal A. Alossaimi (Зохиогч), Yassine Riadi (Зохиогч), Ghaida N. Alnuwaybit (Зохиогч), Shadab Md (Зохиогч), Huda Mohammed Alkreathy (Зохиогч), Engy Elekhnawy (Зохиогч), Mohammed H. Geesi (Зохиогч), Safar M. Alqahtani (Зохиогч), Obaid Afzal (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2024-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Triple-negative breast cancer (TNBC) comprises 10 % to 20 % of breast cancer, however, it is more dangerous than other types of breast cancer, because it lacks druggable targets, such as the estrogen receptors (ER) and the progesterone receptor (PR), and has under expressed receptor tyrosine kinase,...